ChemicalBook--->CAS DataBase List--->1997361-87-1

1997361-87-1

1997361-87-1 Structure

1997361-87-1 Structure
IdentificationBack Directory
[Name]

Lixisenatide acetate
[CAS]

1997361-87-1
[Synonyms]

Lixisenatide acetate (320367-13-3 free base)
Lixisenatide,inhibit,Glucagon Receptor,Lixisenatide acetate (320367 13 3 free base),Inhibitor,Lixisenatide acetate (320367133 free base),GCGR
Chemical PropertiesBack Directory
[solubility ]

Acetonitrile: Slightly soluble
Water: Slightly soluble
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Lixisenatide acetate salt is a useful research chemical used to increase proliferation of pancreatic beta cells in transplate patients with a DYRK1 A inhibitor and a GLP1R agonist.
[References]

[1] CHRISTIAN THORKILDSEN. Glucagon-like peptide 1 receptor agonist ZP10A increases insulin mRNA expression and prevents diabetic progression in db/db mice.[J]. Journal of Pharmacology and Experimental Therapeutics, 2003, 307 2: 490-496. DOI: 10.1124/jpet.103.051987
[2] D TEWS  J E  U Werner. Enhanced protection against cytokine- and fatty acid-induced apoptosis in pancreatic beta cells by combined treatment with glucagon-like peptide-1 receptor agonists and insulin analogues.[J]. Hormone and Metabolic Research, 2008, 40 3: 172-180. DOI: 10.1055/s-2008-1042426
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