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199920-17-7

199920-17-7 Structure

199920-17-7 Structure
IdentificationBack Directory
[Name]

Pyrene phosphoramidite dU
[CAS]

199920-17-7
[Synonyms]

Pyrene phosphoramidite dU
Pyrene-dU-CE Phosphoramidite
[Molecular Formula]

C57H55N4O8P
[MOL File]

199920-17-7.mol
[Molecular Weight]

955.06
Chemical PropertiesBack Directory
[solubility ]

good in dichloromethane and acetonitrile
[pka]

8.21±0.10(Predicted)
[Appearance]

yellowish foam
Hazard InformationBack Directory
[Description]

Pyrene is polycyclic aromatic hydrocarbon which is well-known for its ability to intercalate into DNA. Pyrene features intense blue fluorescence. Its parameters depend strongly on fluorophore microenvironment. Therefore, fluorescence spectra of pyrene are used for the extraction of structural information about site surrounding pyrene. Two pyrenes in close proximity usually form excimers easily detectable by excimer fluorescence. Pyrene can also be a FRET donor to other fluorophores such as perylene.
[Uses]

Pyrene phosphoramidite Du is a click chemistry reagent containing pyrene groups. The pyrene group in Pyrene phosphoramidite Du can be inserted into DNA with strong blue fluorescence.
[Abs/Em Maxima]

260; 282; 365; 392/460 nm
[Fluoresene quantum yield]

~0.1
[Extinction Coefficient]

12600; 21900; 16000; 14200
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