| Identification | Back Directory | [Name]
L-Phenylalanine, glycyl-L-valyl-L-asparaginyl-L-alanyl-L-cysteinyl-L-seryl-L-seryl-L-leucyl-, (9→5)-thiolactone | [CAS]
200010-31-7 | [Synonyms]
L-Phenylalanine, glycyl-L-valyl-L-asparaginyl-L-alanyl-L-cysteinyl-L-seryl-L-seryl-L-leucyl-, (9→5)-thiolactone | [Molecular Formula]
C38H58N10O12S | [MOL File]
200010-31-7.mol | [Molecular Weight]
878.99 |
| Chemical Properties | Back Directory | [Boiling point ]
1424.9±65.0 °C(Predicted) | [density ]
1.37±0.1 g/cm3(Predicted) | [pka]
12?+-.0.70(Predicted) | [Sequence]
Gly-Val-Asn-Ala-Cys-Ser-Ser-Leu-Phe (sulfide bridge: Cys5-Phe9) |
| Hazard Information | Back Directory | [Uses]
AIP-II is a macrocyclic peptide signaling molecule used for quorum sensing, which can be produced be Staphylococcus aureus. AIP-II binds to AgrC-II receptor, regulates the virulence gene expression in Staphylococcus aureus. AIP-II is an antagonist for AgrC-I receptor[1]. | [References]
[1] Tal-Gan Y, et al., Structural characterization of native autoinducing peptides and abiotic analogues reveals key features essential for activation and inhibition of an AgrC quorum sensing receptor in Staphylococcus aureus. J Am Chem Soc. 2013 Dec 11;135(49):18436-44. DOI:10.1021/ja407533e |
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| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Website: |
www.enzo.com |
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