| Identification | Back Directory | [Name]
1(2H)-Pyridinebutanamine, 4-(4-chlorophenyl)-β-cyclopentyl-3,6-dihydro-β-phenyl- | [CAS]
2001072-35-9 | [Synonyms]
DCYM21
DC-YM21
DCYM-21
DC YM21
DC_YM21
DC YM 21
1(2H)-Pyridinebutanamine, 4-(4-chlorophenyl)-β-cyclopentyl-3,6-dihydro-β-phenyl- | [Molecular Formula]
C26H33ClN2 | [MOL File]
2001072-35-9.mol | [Molecular Weight]
409.01 |
| Hazard Information | Back Directory | [Description]
DCYM21, also known as DC_YM21, is an inhibitor of menin-MLL interaction. DCYM21 demonstrates potent and selective blockage of proliferation and induces both cell cycle arrest and differentiation of leukemia cells harboring MLL translocations. | [Uses]
DC_YM21 is an inhibitor of menin-MLL interaction with potent and selective proliferation blocking activity. DC_YM21 can induce cell cycle arrest and differentiation of leukemia cells carrying MLL translocation. DC_YM21 shows potential application value in inhibiting MLL leukemia[1]. | [References]
[1] Identification of novel small-molecule inhibitors targeting menin-MLL interaction, repurposing the antidiarrheal loperamide |
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