| Identification | Back Directory | [Name]
L-Alaninamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-alanyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- | [CAS]
2003260-14-6 | [Synonyms]
L-Alaninamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-alanyl-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- | [Molecular Formula]
C30H33N5O10 | [MOL File]
2003260-14-6.mol | [Molecular Weight]
623.61 |
| Hazard Information | Back Directory | [Uses]
Mal-Ala-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | [IC 50]
Cleavable Linker | [References]
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. DOI:10.1038/nrd.2016.268 |
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