Identification | Back Directory | [Name]
uvarigrin | [CAS]
200563-11-7 | [Synonyms]
uvarigrin 2(5H)-Furanone, 3-[(13S,15R)-13,15-dihydroxy-15-[(2R,5R)-tetrahydro-5-[(1R)-1-hydroxytridecyl]-2-furanyl]pentadecyl]-5-methyl-, (5S)- | [Molecular Formula]
C37H68O6 | [MDL Number]
MFCD32202747 | [MOL File]
200563-11-7.mol | [Molecular Weight]
608.93 |
Chemical Properties | Back Directory | [Boiling point ]
741.3±35.0 °C(Predicted) | [density ]
1.008±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
14.20±0.20(Predicted) |
Hazard Information | Back Directory | [Uses]
Uvarigrin, isolated from the roots of Uvaria calamistrata, induces tumor multidrug resistance cell apoptosis and triggers Caspase-9 activation[1][2]. | [storage]
Store at -20°C | [References]
[1] Zhou GX, et al. Calamistrins A and B, two new cytotoxic monotetrahydrofuran annonaceous acetogenins from Uvaria calamistrata. J Nat Prod. 1999 Feb;62(2):261-4. DOI:10.1021/np980334q [2] Li YF, et al. Induction of apoptosis of tumor multidrug resistance cell by uvarigrin and its mechanism. Yao Xue Xue Bao. 2006 Mar;41(3):252-6. PMID:16758998 |
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