| Identification | Back Directory | [Name]
C-11 | [CAS]
2007965-97-9 | [Synonyms]
C 11,C11
L-Isoleucinamide, 1,2-dimethyl-D-prolyl-N-[(1R,3R)-3-(acetyloxy)-3-[4-[[[(1R,3S)-1-[(4-aminophenyl)methyl]-3-carboxybutyl]amino]carbonyl]-2-thiazolyl]-1-(1-methylethyl)propyl]-N-methyl- | [Molecular Formula]
C38H58N6O7S | [MDL Number]
MFCD32174060 | [MOL File]
2007965-97-9.mol | [Molecular Weight]
742.97 |
| Hazard Information | Back Directory | [Uses]
C-11 is a tubulin inhibitor and acts as an ADC cytotoxin, displays cytotoxicity for carcinoma cell lines[1]. | [IC 50]
Traditional Cytotoxic Agents | [References]
[1] Leverett CA, et al. Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads. ACS Med Chem Lett. 2016 Aug 26;7(11):999-1004. DOI:10.1021/acsmedchemlett.6b00274 |
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