| Identification | Back Directory | [Name]
Cell-permeable Caspase-1 Inhibitor I trifluoroacetate salt | [CAS]
201608-12-0 | [Synonyms]
Cell-permeable Caspase-1 Inhibitor I
Cell-permeable Caspase-1 Inhibitor I trifluoroacetate salt
Cell-permeable Caspase-1 Inhibitor I trifluoroacetate salt Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Tyr-Val-Ala-Asp-aldehyde (pseudo acid) trifluoroacetate salt | [Molecular Formula]
C97H160N20O24 | [MDL Number]
MFCD01322992 (net) | [MOL File]
201608-12-0.mol | [Molecular Weight]
1990.43 |
| Chemical Properties | Back Directory | [Boiling point ]
1970.9±65.0 °C(Predicted) | [density ]
1.193±0.06 g/cm3(Predicted) | [pka]
4.20±0.10(Predicted) | [Sequence]
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Tyr-Val-Ala-Asp-CHO |
| Hazard Information | Back Directory | [Uses]
Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable caspase-1 inhibitor that has antitumor activity[1]. | [IC 50]
Caspase-1 | [References]
[1] S Schlosser, et al. Inhibition of caspase-1 induces cell death in pancreatic carcinoma cells and potentially modulates expression levels of bcl-2 family proteins. FEBS Lett. 2001 Feb 23;491(1-2):104-8. DOI:10.1016/s0014-5793(01)02144-5 |
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| Company Name: |
Carbosynth
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+86 512 6260 5585 |
| Website: |
www.carbosynth.com |
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