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201995-58-6

201995-58-6 Structure

201995-58-6 Structure
IdentificationBack Directory
[Name]

(Lys1,Arg1,Leu2)-VIP (1-7)-GRF (8-27)
[CAS]

201995-58-6
[Synonyms]

(Lys1?,Arg1?,Leu2?)-VIP (1-7)-GRF (8-27)
L-Leucinamide, L-histidyl-L-seryl-L-α-aspartyl-L-alanyl-L-valyl-L-phenylalanyl-L-threonyl-L-asparaginyl-L-seryl-L-tyrosyl-L-arginyl-L-lysyl-L-valyl-L-leucyl-L-lysyl-L-arginyl-L-leucyl-L-seryl-L-alanyl-L-arginyl-L-lysyl-L-leucyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-isoleucyl-
[Molecular Formula]

C142H240N44O38
[MDL Number]

MFCD19443515
[MOL File]

201995-58-6.mol
[Molecular Weight]

3171.75
Chemical PropertiesBack Directory
[density ]

1.44±0.1 g/cm3(Predicted)
[form ]

Solid
[color ]

White to off-white
[Sequence]

His-Ser-Asp-Ala-Val-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Lys-Arg-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-NH2
Hazard InformationBack Directory
[Uses]

[K15,R16,L27]VIP(1-7)/GRF(8-27), a VIP1 selective agonist, exhibits IC50 values of binding of 2 nM, 1 nM, 30,000 nM for the human VIP1, rat VIP1, rat VIP2 receptors, respectively[1]. VIP: VASOACTIVE Intestinal Polypeptide
[References]

[1] P Gourlet, et al. Development of high affinity selective VIP1 receptor agonists. Peptides. 1997;18(10):1539-45. DOI:10.1016/s0196-9781(97)00228-3
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