| Identification | Back Directory | [Name]
CHOLINE CHLORIDE (1,2-13C2, 99%) | [CAS]
202190-49-6 | [Synonyms]
CHOLINE CHLORIDE (1,2-13C2, 99%) | [Molecular Formula]
C5H14ClNO | [MDL Number]
MFCD00143967 | [MOL File]
202190-49-6.mol | [Molecular Weight]
139.624 |
| Hazard Information | Back Directory | [Uses]
Choline-13C2 (chloride) is the 13C labeled Choline chloride[1]. Choline chloride is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders[2][3]. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] M Q Holmes-McNary, et al. Apoptosis is induced by choline deficiency in fetal brain and in PC12 cells. Brain Res Dev Brain Res. 1997 Jul 18;101(1-2):9-16. DOI:10.1016/s0165-3806(97)00044-8
[3] T J Rowley, et al. Antinociceptive and anti-inflammatory effects of choline in a mouse model of postoperative pain. Br J Anaesth. 2010 Aug105(2):201-7. DOI:10.1093/bja/aeq113 |
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