ChemicalBook--->CAS DataBase List--->2022956-62-1

2022956-62-1

2022956-62-1 Structure

2022956-62-1 Structure
IdentificationBack Directory
[Name]

T-Peptide
[CAS]

2022956-62-1
[Synonyms]

T-Peptide
Ac-VQIVYKRRRRRRRRR-NH2
L-Argininamide, N-acetyl-D-valyl-D-glutaminyl-D-isoleucyl-D-valyl-D-tyrosyl-D-lysyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-
[Molecular Formula]

C92H171N45O18
[MOL File]

2022956-62-1.mol
[Molecular Weight]

2195.63
Chemical PropertiesBack Directory
[density ]

1.50±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
Hazard InformationBack Directory
[Uses]

T-peptide, a Tuftsin analog, can be used for the research of human immunodeficiency virus (HIV) infection. T-peptide prevents cellular immunosuppression and improves survival rate in septic mice. T-peptide also can inhibit the growth of residual tumor cells after surgical resection[1][2].
[storage]

Store at -20°C
[References]

[1] Simpson DM, et, al. Peptide T in the treatment of painful distal neuropathy associated with AIDS: results of a placebo-controlled trial. The Peptide T Neuropathy Study Group. Neurology. 1996 Nov;47(5):1254-9. DOI:10.1212/wnl.47.5.1254
[2] Gao YL, et, al. Tuftsin-derived T-peptide prevents cellular immunosuppression and improves survival rate in septic mice. Sci Rep. 2015 Nov 18;5:16725. DOI:10.1038/srep16725
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