| Identification | Back Directory | [Name]
1,2,3-TRI[CIS-9-HEXADECENOYL]GLYCEROL | [CAS]
20246-55-3 | [Synonyms]
TRIPALMITOLEIN
Trihexadecenoin
glyceryl tripalmitoleate
GLYCERYL TRIPALIMITOLEATE
TRIPALMITOLEIN (C16:1, [CIS]-9)
L-Glycerol 1,2,3-tripalmitoleate
1,2,3-Propanetriol tripalmitoleate
1,2,3-Tripalmitoleoyl-rac-glycerol
Glycerol tris[(9Z)-9-hexadecenoate]
1,2,3-TRI[CIS-9-HEXADECENOYL]GLYCEROL
tripalmitolein (C16:1,-cis-9) grade I
Glyceryl tripalmitoleate >=98%, liquid
Glyceryl tripalmitoleate,Tripalmitolein
1-O,2-O,3-O-Tri[(9Z)-9-hexadecenoyl]-L-glycerol
9-Hexadecenoic acid, 1,1',1''-(1,2,3-propanetriyl) ester, (9Z,9'Z,9''Z)- | [Molecular Formula]
C51H92O6 | [MDL Number]
MFCD00056313 | [MOL File]
20246-55-3.mol | [Molecular Weight]
801.27 |
| Chemical Properties | Back Directory | [Boiling point ]
765.9±50.0 °C(Predicted) | [density ]
0.929±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
Chloroform: soluble | [form ]
liquid | [biological source]
synthetic | [LogP]
20.387 (est) |
| Hazard Information | Back Directory | [Description]
1,2,3-Tripalmitoleoyl glycerol is a triacylglycerol that contains palmitoleic acid (Item Nos. 10009871 | 21911) at the sn-1, sn-2, and sn-3 positions. It reduces red blood cell deformability in a concentration-dependent manner in a Reid''s filtration assay. Hepatic levels of 1,2,3-tripalmitoleoyl glycerol are increased in the JAK2L mouse model of hepatic steatosis. 1,2,3-Tripalmitoleoyl glycerol plasma levels are decreased in renal patients before dialysis. | [Uses]
1,2,3-Tripalmitoleoyl-rac-glycerol is a triacylglycerol containing palmitoleic acid at the sn-1, sn-2 and sn-3 positions. It reduces erythrocyte deformability in a concentration-dependent manner in the Reid filtration assay. Hepatic levels of 1,2,3-tripalmitoleoyl-rac-glycerol are increased in a JAK2L mouse model of hepatic steatosis. 1,2,3-Tripalmitoleoyl-rac-glycerol plasma levels are reduced in patients with predialysis renal disease. | [Definition]
ChEBI: 1,2,3-tripalmitoleoylglycerol is a triglyceride formed by acylation of the three hydroxy groups of glycerol with palmitoleic acid. It is functionally related to a palmitoleic acid. | [IC 50]
Human Endogenous Metabolite | [References]
[1] C.Y. HONG . Effect of triacylglycerols on erythrocyte deformability in vitro[J]. Prostaglandins, leukotrienes, and essential fatty acids, 1993, 48 5: Pages 351-353. DOI: 10.1016/0952-3278(93)90114-c
[2] CAMELLA G. WILSON. Hepatocyte-Specific Disruption of CD36 Attenuates Fatty Liver and Improves Insulin Sensitivity in HFD-Fed Mice.[J]. Endocrinology, 2016, 114 1: 570-585. DOI: 10.1210/en.2015-1866
[3] DIANA M LEE. Oxidative stress and inflammation in renal patients and healthy subjects.[J]. PLoS ONE, 2011: e22360. DOI: 10.1371/journal.pone.0022360 |
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