| Identification | Back Directory | [Name]
CIS-4-AMINO-5-CHLORO-2-METHOXY-N-(3-METHOXY-PIPERIDIN-4-YL)-BENZAMIDE | [CAS]
202590-69-0 | [Synonyms]
Ticalopride
202590-69-0
NORCISAPRIDE
Unii-qng273A81o
Ticalopride [inn]
CIS-4-AMINO-5-CHLORO-2-METHOXY-N-(3-METHOXY-PIPERIDIN-4-YL)-BENZAMIDE
4-amino-5-chloro-2-methoxy-N-((3S,4R)-3-methoxypiperidin-4-yl)benzamide
Benzamide, 4-amino-5-chloro-2-methoxy-N-[(3S,4R)-3-methoxy-4-piperidinyl]- | [Molecular Formula]
C14H20ClN3O3 | [MDL Number]
MFCD07784009 | [MOL File]
202590-69-0.mol | [Molecular Weight]
313.78 |
| Hazard Information | Back Directory | [Uses]
(+)-Norcisapride (Ticalopride) is a potent 5-HT4 agonist and a 5-HT3 antagonist. (+)-Norcisapride has activity in animals models of constipation[1]. | [IC 50]
5-HT4 Receptor; 5-HT3 Receptor | [References]
[1] Liming Shao, et al. mu-Opioid/5-HT4 dual pharmacologically active agents-efforts towards an effective opioid analgesic with less GI and respiratory side effects (Part I). Bioorg Med Chem Lett. 2009 Oct 1;19(19):5679-83. DOI:10.1016/j.bmcl.2009.08.016 |
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