| Identification | Back Directory | [Name]
1-METHYL-1H-INDOLE-6-CARBOXYLIC ACID 97 | [CAS]
202745-73-1 | [Synonyms]
CC 44201
6-Carboxy-1-methyl-1H-indole
1-methyl-6-indolecarboxylic acid
1-METHYL-1H-INDOLE-6-CARBOXYLIC ACID
1H-Indole-6-carboxylic acid, 1-methyl-
1-METHYL-1H-INDOLE-6-CARBOXYLIC ACID 97
1-Methyl-1H-indole-6-carboxylic acid 97%
1-methyl-1H-indole-6-carboxylic acid(SALTDATA: FREE) | [Molecular Formula]
C10H9NO2 | [MDL Number]
MFCD08690250 | [MOL File]
202745-73-1.mol | [Molecular Weight]
175.184 |
| Chemical Properties | Back Directory | [Melting point ]
197 °C | [Boiling point ]
389.0±15.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
solid | [pka]
4.53±0.30(Predicted) | [color ]
Pale yellow | [InChI]
1S/C10H9NO2/c1-11-5-4-7-2-3-8(10(12)13)6-9(7)11/h2-6H,1H3,(H,12,13) | [InChIKey]
DJQOGNYSBOIJKE-UHFFFAOYSA-N | [SMILES]
Cn1ccc2ccc(cc12)C(O)=O |
| Hazard Information | Back Directory | [Synthesis]
Step 2: Synthesis of 1-methyl-1H-indole-6-carboxylic acid (167). Methyl 1-methyl-1H-indole-6-carboxylate (166, 1.24 mmol) was reacted with sodium hydroxide (0.59 g, 14.88 mmol) in a solvent mixture of methanol/THF/water (2:2:1, 7.5 mL) with stirring for 36 h at room temperature. A precipitate was generated during the reaction and the precipitate was collected by filtration followed by lyophilization overnight to afford the target product 1-methyl-6-indolecarboxylic acid (167, 0.54 g, 99% yield). Mass spectral data: calculated (Calc) 175.06, observed (Obs) 176.1. | [References]
[1] Patent: WO2005/30704, 2005, A1. Location in patent: Page/Page column 199-200
[2] Patent: WO2008/65508, 2008, A1. Location in patent: Page/Page column 32
[3] Heterocycles, 2006, vol. 67, # 2, p. 643 - 653 |
|
| Company Name: |
Biokitchen
|
| Tel: |
021-021-021-31663258 13795219287 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList20174/0_EN.htm |
|