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20283-69-6

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20283-69-6 Structure

20283-69-6 Structure
IdentificationBack Directory
[Name]

niddamycin
[CAS]

20283-69-6
[Synonyms]

F3463
F-3463
F 3463
niddamycin
9-Deoxy-9-oxoleucomycin V 4''-(3-methylbutanoate)
Leucomycin V, 9-deoxy-9-oxo-, 4B-(3-methylbutanoate)
[Molecular Formula]

C40H65NO14
[MDL Number]

MFCD01747790
[MOL File]

20283-69-6.mol
[Molecular Weight]

783.94
Chemical PropertiesBack Directory
[Boiling point ]

876.9±65.0 °C(Predicted)
[density ]

1.21±0.1 g/cm3(Predicted)
[pka]

13.06±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

Niddamycin, a macrolide antibiotic, binds 50S ribosomal subunits to inhibit protein synthesis[1].
[References]

[1] S J Kakavas, et al. Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis. J Bacteriol. 1997 Dec;179(23):7515-22. DOI:10.1128/jb.179.23.7515-7522.1997
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