| Identification | Back Directory | [Name]
N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-CERAMIDE | [CAS]
202850-01-9 | [Synonyms]
C12 NBD-CERAMIDE
N-(NBD-AMINOLAUROYL)CERAMIDE
N-C12-NBD-L-THREO-SPHINGOSINE
C12 NBD Ceramide (d18:1/12:0)
N-C12-NBD-D-ERYTHRO-SPHINGOSINE
N-DODECANOYL-NBD-L-THREO-SPHINGOSINE
N-DODECANOYL-NBD-D-ERYTHRO-SPHINGOSINE
N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-CERAMIDE
N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-D-ERYTHROSPINGOSINE
N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)aMino]dodecanoyl]-D-erythro-sphingosine
C12-NBD Ceramide, N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-ceramide
N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-D-ERYTHRO-SPHINGOSINE;C12-NBD CERAMIDE
Dodecanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-12-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]- | [Molecular Formula]
C36H61N5O6 | [MDL Number]
MFCD02259239 | [MOL File]
202850-01-9.mol | [Molecular Weight]
659.9 |
| Chemical Properties | Back Directory | [Melting point ]
92-93 °C | [density ]
1.103±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml | [form ]
A crystalline solid | [pka]
13.54±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
C12-NBD Ceramide or N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-D-erythro-sphingosine has been used as a substrate in ceramidase activity assay. It is also suitable for the lipid binding assays and in cell culture experiments for endothelial cells to determine the pro-apoptotic intracellular ceramide generation. | [Definition]
ChEBI: N-[12-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-ceramide is an organic molecular entity and a ceramide. | [Biological Activity]
Ceramide is one of the products of sphingolipid metabolism. The members of ceramide synthase family are responsible for its synthesis. Each ceramide synthesized differs in its acyl chain length. Ceramides possess a wide range of functionsassociated with apoptosiscancer inhibition and chemotherapy. Its action is also related to neurodegenerative diseases. |
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