| Identification | Back Directory | [Name]
SCH-60057 | [CAS]
203061-35-2 | [Synonyms]
SCH-60057
3,7,11,15,19,23,27,31,35-nonamethyl-2E,6E,10E,34-hexatriacontatetraene-1,15,19,23,27,31-hexol
2,6,10,34-Hexatriacontatetraene-1,15,19,23,27,31-hexol, 3,7,11,15,19,23,27,31,35-nonamethyl-, (2E,6E,10E)- | [Molecular Formula]
C45H84O6 | [MDL Number]
MFCD27968229 | [MOL File]
203061-35-2.mol | [Molecular Weight]
721.14 |
| Chemical Properties | Back Directory | [Boiling point ]
800.8±65.0 °C(Predicted) | [density ]
0.987±0.06 g/cm3(Predicted) | [solubility ]
Dichloromethane: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
A solid | [pka]
14.42±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
SCH 60057 is a fungal metabolite that has been found in Acremonium and a neurokinin receptor (NK) antagonist (IC50s = 6 and 12 μM for NK1 and NK2, respectively). | [Uses]
SCH 60057 (Compound 7) is a neurokinin (NK) receptor inhibitor that can be isolated from Acremonium sp., with IC50 values of 6 μM and 12 μM for NK1 and NK2, respectively[1]. | [References]
[1] Hegde VR, et al. Neurokinin receptor inhibitors: fermentation, isolation, physico-chemical properties, structure and biological activity. J Antibiot (Tokyo). 1997 Dec;50(12):983-91. DOI:10.7164/antibiotics.50.983 |
|
|