| Identification | Back Directory | [Name]
Solamargine | [CAS]
20311-51-7 | [Synonyms]
NSC 407810
Solamargin
SOLAMERGINE
δ-Solanigrine
α-Solamargine
Solamargine, >98%
Solamargine 20311-51-7
2)-O-[6-deoxy-a-L-Mannopyranosyl-(1®
b-D-Glucopyranoside, (3b,22a,25R)-spirosol-5-en-3-yl O-6-deoxy-a-L-Mannopyranosyl-(1®
spirosol-5-en-3-yl 6-deoxyhexopyranosyl-(1->2)-[6-deoxyhexopyranosyl-(1->4)]hexopyranoside
[(22R,25R)-Spirosola-5-ene-3β-yl]2-O,4-O-bis(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
(3β,22α,25R)-Spirosol-5-en-3-yl 6-deoxy-α-L-mannopyranosyl-(1→2)-[6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside
b-D-Glucopyranoside, (3b,22a,25R)-spirosol-5-en-3-yl O-6-deoxy-a-L-mannopyranosyl-(12)-O-[6-deoxy-a-L-mannopyranosyl-(14)]-
β-D-Glucopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-
(3beta,22alpha,25R)-spirosol-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-[6-deoxy-alpha-L-mannopyranosyl-(1-4)]-beta-D-glucopyranoside | [Molecular Formula]
C45H73NO15 | [MDL Number]
MFCD30207844 | [MOL File]
20311-51-7.mol | [Molecular Weight]
868.06 |
| Chemical Properties | Back Directory | [Melting point ]
301 °C | [density ]
1.38 | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
12?+-.0.70(Predicted) | [color ]
Light Beige |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It is derived from the fruit of Solanum aviculare Forst. | [Uses]
α-Solamargine is a steroidal glycosyl-alkaloid which displays inactivation of PI3-L/Akt and reduction for SP1 and p65 in the suppression of human lung cancer cells. | [Definition]
ChEBI: Solamargine is an azaspiro compound, a steroid and an oxaspiro compound. | [in vivo]
Solamargine (10 mg/kg; intragastric administration; once daily for 8 days) exhibits an antitumor effect and promotes the apoptosis of GC in vivo[4]. | Animal Model: | Female specific pathogen-free BALB/c nude mice weighing 18-20 g (6-8-weeks-old)[4] | | Dosage: | 10 mg/kg | | Administration: | Intragastric administration; once daily for 8 days
| | Result: | Tumor growth was significantly inhibited .
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