| Identification | Back Directory | [Name]
3-hydroxystigmast-5-en-7-one | [CAS]
2034-74-4 | [Synonyms]
7-Oxo-β-sitosterol
7-Oxo-beta-sitosterol
3-hydroxystigmast-5-en-7-one
Stigmast-5-en-7-one,3-hydroxy-, (3b)-
Stigmast-5-en-7-one, 3-hydroxy-, (3β)- | [Molecular Formula]
C29H48O2 | [MOL File]
2034-74-4.mol | [Molecular Weight]
428.69 |
| Chemical Properties | Back Directory | [Melting point ]
120-123 °C | [Boiling point ]
536.1±29.0 °C(Predicted) | [density ]
1.01±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMF: 12 mg/ml,Ethanol: 3 mg/ml | [form ]
Powder | [pka]
14.68±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
7-Ketositosterol is a phytosterol isolated from the fruits of the mulberry tree (Morus alba L.). 7-Ketositosterol can significantly inhibit Cisplatin (HY-17394)-induced apoptosis in LLC-PK1 cells and has the potential to improve Cisplatin-induced nephrotoxicity[1]. | [Definition]
ChEBI: 3-Hydroxystigmast-5-en-7-one is a steroid. It derives from a hydride of a stigmastane. | [References]
[1] Lee D, et al. Identification of Renoprotective Phytosterols from Mulberry (Morus alba) Fruit against Cisplatin-Induced Cytotoxicity in LLC-PK1 Kidney Cells. Plants (Basel). 2021 Nov 17;10(11):2481. DOI:10.3390/plants10112481 |
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