| Identification | Back Directory | [Name]
2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- | [CAS]
2034181-36-5 | [Synonyms]
AMPA receptor modulator-2
2(3H)-Benzothiazolone, 6-[2,5-bis(trifluoromethyl)-3H-imidazo[4,5-b]pyridin-3-yl]- | [Molecular Formula]
C15H6F6N4OS | [MOL File]
2034181-36-5.mol | [Molecular Weight]
404.29 |
| Chemical Properties | Back Directory | [density ]
1.79±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 250 mg/mL (618.37 mM; Need ultrasonic)| | [form ]
Solid | [pka]
9.56±0.20(Predicted) | [color ]
White to off-white | [Water Solubility ]
Water : < 0.1 mg/mL (insoluble) |
| Hazard Information | Back Directory | [Biological Activity]
AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. | [References]
[1]. BERRY CYNTHIA G B (US), et al. AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS. Patent. WO2016176460. |
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