| Identification | Back Directory | [Name]
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid | [CAS]
203640-27-1 | [Synonyms]
R-3-(1H-Indol-3-yl)-2-(5-(p-tolyleth ynyl)thiophene-2
D-Tryptophan, N-[[5-[2-(4-methylphenyl)ethynyl]-2-thienyl]sulfonyl]-
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid
(2R)-3-(1H-indol-3-yl)-2-{5-[2-(4-methylphenyl)ethynyl]thiophene-2-sulfonamido}propanoic acid
(2R)-3-(1H-indol-3-yl)-2-[[5-[2-(4-methylphenyl)ethynyl]thiophen-2-yl]sulfonylamino]propanoic acid | [Molecular Formula]
C24H20N2O4S2 | [MOL File]
203640-27-1.mol | [Molecular Weight]
464.56 |
| Chemical Properties | Back Directory | [Boiling point ]
745.7±70.0 °C(Predicted) | [density ]
1.47±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
Aqueous Base (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
3.29±0.10(Predicted) | [color ]
Pale Beige to Light Beige |
| Hazard Information | Back Directory | [Description]
S-3304 is a sulfonamide derivative that acts as a matrix metalloproteinase inhibitor. | [Uses]
S 3304, is a novel matrix metalloproteinases (MMP) inhibitor specific for MMP-2 and MMP-9. | [in vivo]
In vivo pharmacologic studies have shown that the oral administration of S 3304, at a dose range of 20 to 200 mg/kg, inhibits angiogenesis, artificially induced in mice by the dorsal air-sac method. Similar oral doses of S 3304 result in potent inhibition of metastatic lung colonization of Lewis murine lung carcinoma injected via tail vein and liver metastasis of C-1H human colon cancer implanted into the spleen[1]. | [IC 50]
MMP-9 |
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| Company Name: |
Shanghai GL Peptide Ltd.
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+86-21-61263340; 17609490614 13764994101 |
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https://www.chemicalbook.com/supplier/10480342/ |
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