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2040055-84-1

2040055-84-1 Structure

2040055-84-1 Structure
IdentificationBack Directory
[Name]

PF-4363467
[CAS]

2040055-84-1
[Synonyms]

PF-4363467
PF 04363467
Benzenesulfonamide, N-[4-[(2R)-4-ethyl-2-morpholinyl]-2-methylphenyl]-4-(1-methylethyl)-
[Molecular Formula]

C22H30N2O3S
[MOL File]

2040055-84-1.mol
[Molecular Weight]

402.55
Chemical PropertiesBack Directory
[Boiling point ]

523.8±60.0 °C(Predicted)
[density ]

1.164±0.06 g/cm3(Predicted)
[pka]

8.79±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

PF-4363467, a dopamine D3/D2 receptor antagonist, attenuates opioid drug-seeking behavior without concomitant D2 side effects. PF-4363467 exhibits Ki values of 3.1 nM and 692 nM for D3R and D2R[1].
[IC 50]

D3 Receptor: 3.1 nM (Ki); D2 Receptor: 692 nM (Ki)
[References]

[1] Dopamine D3/D2 Receptor Antagonist PF-4363467 Attenuates Opioid Drug-Seeking Behavior without Concomitant D2 Side Effects. ACS Chem Neurosci. 2017 Jan 18;8(1):165-177. DOI:10.1021/acschemneuro.6b00297
2040055-84-1 suppliers list
Company Name: Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd  
Telephone: 15317229551
Website: https://www.ureiko.com
Company Name: TargetMol  
Telephone: 400-821-0310 15002144251
Website: www.targetmol.cn/
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