| Identification | Back Directory | [Name]
2',3'-O-Isopropylidene 5-hydroxyuridine | [CAS]
20406-82-0 | [Synonyms]
2',3'-Isopropylidene-5-hydroxyuridine
2',3'-O-Isopropylidene 5-hydroxyuridine
2',3'-Di-O-isopropylidene 5-hydroxyuridine
5-Hydroxy-2',3'-O-(1-methylethylidene)uridine
Uridine, 5-hydroxy-2',3'-O-(1-methylethylidene)-
5-hydroxy-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione | [Molecular Formula]
C12H16N2O7 | [MDL Number]
MFCD22666327 | [MOL File]
20406-82-0.mol | [Molecular Weight]
300.26 |
| Hazard Information | Back Directory | [Uses]
2’,3’-Isopropylidene-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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