| Identification | Back Directory | [Name]
RTI 4229-336 | [CAS]
204069-50-1 | [Synonyms]
RTI 336
RTI-336
RTI 4229-336
(1R,2S,3S,5S)-3-(4-Chlorophenyl)-8-Methyl-2-[3-(4-Methylphenyl)-5-isoxazolyl]-8-azabicyclo[3.2.1]octane Hydrochloride
[1R-(exo,exo)]-3-(4-Chlorophenyl)-8-Methyl-2-[3-(4-Methylphenyl)-5-isoxazolyl]-8-azabicyclo[3.2.1]octane Hydrochloride | [Molecular Formula]
C23H24Cl2N2O | [MDL Number]
MFCD09970296 | [MOL File]
204069-50-1.mol | [Molecular Weight]
415.355 |
| Hazard Information | Back Directory | [Uses]
RTI-336 is a a phenyltropane cocaine analog that acts selective dopamine reuptake inhibitor (1,2,3). RTI-336 binds to the dopamine transporter with around 20 times the affinity of cocaine but produces relatively mild stimulant effects. RTI-336 is a potential candidate for pharmacotherapy for treating cocaine addiction. | [Uses]
RTI-336 is a a phenyltropane cocaine analog that acts selective dopamine reuptake inhibitor. RTI-336 binds to the dopamine transporter with around 20 times the affinity of cocaine but produces relativ
ely mild stimulant effects. RTI-336 is a potential candidate for pharmacotherapy for treating cocaine addiction. | [in vivo]
RTI 336 (3 mg/kg; sc; 30 min pretreatment) significantly decreases the number of infusions of addictive agent in Lewis rats[1].
RTI 336 (3 mg/kg; ip; 30 min pretreatment) decreases response rates (lever presses/s) induced by addictive agent in Lewis rats[1].
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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