| Chemical Properties | Back Directory | [density ]
1.432±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
3.015±0.10(predicted) | [Sequence]
Gly-Arg-Phe-Leu-Thr-Gly-Gly-Thr-Gly-Arg-Leu-Leu-Arg-Ile-Ser |
| Hazard Information | Back Directory | [Uses]
PSMA-1 is a PSMA targeting peptide (GRFLTGGTGRLLRIS) and can be used for for targeted delivery of glucose-regulated protein (GRP)-silencing siRNAs in PCa cells. PSMA-1 is selected and polyarginine sequences R6 or R9 were added at the C terminus to generate the CTPs. FITC labeling of the peptide with an aminohexanoic acid (Ahx) linker at the N terminus produced FITC-PSMA-1，to track PSMA binding on PCa cells[1]. | [References]
[1] Christopher N Cultrara, et al. Size Matters: Arginine-Derived Peptides Targeting the PSMA Receptor Can Efficiently Complex but Not Transfect siRNA. Mol Ther Nucleic Acid. 019 Dec 6:18:863-870. DOI:10.1016/j.omtn.2019.10.013 |
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