| Identification | Back Directory | [Name]
DriMentine A | [CAS]
204398-90-3 | [Synonyms]
DriMentine A
2H-Pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione, 10b-[[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]methyl]-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-, (3S,5aS,10bS,11aS)- | [Molecular Formula]
C32H45N3O2 | [MDL Number]
MFCD33021216 | [MOL File]
204398-90-3.mol | [Molecular Weight]
503.72 |
| Chemical Properties | Back Directory | [Boiling point ]
671.1±55.0 °C(Predicted) | [density ]
1.16±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
A solid | [pka]
13.39±0.60(Predicted) |
| Hazard Information | Back Directory | [Description]
Drimentine A is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. It is active against Gram-positive and Gram-negative bacteria, fungi, and yeast and has anthelmintic properties. | [Uses]
Drimentine A belongs to a novel class of antibiotics, possessing a new terpenylated diketopiperazine structure, with antibiotic, antifungal and anthelmintic activity. The mode of action of drimentine A has received little attention to date. | [Uses]
Drimentine A is a novel antibiotic with a terpenylated diketopiperazine structure. | [References]
[1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras. |
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