| Identification | Back Directory | [Name]
Benzamide, 4-amino-N-[2-(4-benzoyl-1-piperidinyl)ethyl]-N-3-pyridinyl- | [CAS]
204643-75-4 | [Synonyms]
5-HT2A antagonist 1
Benzamide, 4-amino-N-[2-(4-benzoyl-1-piperidinyl)ethyl]-N-3-pyridinyl- | [Molecular Formula]
C26H28N4O2 | [MDL Number]
MFCD31544415 | [MOL File]
204643-75-4.mol | [Molecular Weight]
428.53 |
| Chemical Properties | Back Directory | [Boiling point ]
655.0±55.0 °C(Predicted) | [density ]
1.226±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
7.83±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
5-HT2A antagonist 1 is a 5-HT2A antagonist extracted from patent US5728835A and JP 1007727. 5-HT2A antagonist 1 may be useful in treatment of gastrointestinal disorders circulatory disorders. | [Biological Activity]
5-HT2A antagonist 1 is a 5-HT2A antagonist from patents US5728835A and JP 1007727. It has potential for cardiovascular research. | [in vitro]
Please refer to patent US5728835A and JP 1007727 for more information. | [target]
| [IC 50]
5-HT2A Receptor | [storage]
Store at -20°C | [References]
[1] Aoki Tsuyoshi, et al. Substituted cyclic amine compound, production process thereof and pharmaceutical composition for circulatory organ use containing the same. US5728835A
[2] Preparation of 3-?pyridylamines as 5-?HT2 receptor antagonists for treatment of circulatory disorders |
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