| Identification | Back Directory | [Name]
4',5'-Didehydro-5'-deoxyadenosine | [CAS]
20535-04-0 | [Synonyms]
CALCIUM BIS(CYCLOHEXYLSULFAMATE)
4',5'-Didehydro-5'-deoxyadenosine
Adenosine, 4',5'-didehydro-5'-deoxy-
4’,5’-Didehydro-5’-deoxyadenosine, 1-(5-Deoxy-beta-D-erythro-pent-4-enofuranosyl)adenine | [Molecular Formula]
C10H11N5O3 | [MOL File]
20535-04-0.mol | [Molecular Weight]
249.23 |
| Chemical Properties | Back Directory | [Melting point ]
195-196 °C (decomp)(Solv: methanol (67-56-1); acetone (67-64-1)) | [Boiling point ]
591.1±60.0 °C(Predicted) | [density ]
1.91±0.1 g/cm3(Predicted) | [pka]
13.15±0.60(Predicted) |
| Hazard Information | Back Directory | [Uses]
4′,5′-Didehydro-5′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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