| Identification | Back Directory | [Name]
1H-Inden-1-one, 2,3-dihydro-7-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-, (2E)- | [CAS]
2054199-25-4 | [Synonyms]
TNF-α-IN-9
1H-Inden-1-one, 2,3-dihydro-7-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-, (2E)- | [Molecular Formula]
C17H14O4 | [MOL File]
2054199-25-4.mol | [Molecular Weight]
282.29 |
| Hazard Information | Back Directory | [Uses]
TNF-α-IN-9 (compound 48) is a analog of NDM-1 inhibitor-3 (HY-150758). TNF-α-IN-9 is a TNF-α inhibitor. TNF-α-IN-9 shows low inhibitory activity[1]. | [References]
[1] Kadayat TM, et al. Discovery and structure-activity relationship studies of 2-benzylidene-2,3-dihydro-1H-inden-1-one and benzofuran-3(2H)-one derivatives as a novel class of potential therapeutics for inflammatory bowel disease. Eur J Med Chem. 2017 Sep 8;137:575-597. DOI:10.1016/j.ejmech.2017.06.018 |
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