| Identification | Back Directory | [Name]
Tri(Amino-PEG5-amide)-amine TFA salt | [CAS]
2055013-52-8 | [Synonyms]
CUN 13528
Tri(Amino-PEG5-amide)-amine TFA salt | [Molecular Formula]
C45H93N7O18 | [MDL Number]
MFCD28142444 | [MOL File]
2055013-52-8.mol | [Molecular Weight]
1020.26 |
| Chemical Properties | Back Directory | [Boiling point ]
1025.2±65.0 °C(Predicted) | [density ]
1.130±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DMF | [pka]
15.11±0.46(Predicted) |
| Hazard Information | Back Directory | [Description]
Tri(Amino-PEG5-amide)-amine is a water soluble PEG linker. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. | [Uses]
Tri(Amino-PEG5-amide)-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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