| Identification | Back Directory | [Name]
(+)-Biotin-PEG6-NHS Ester | [CAS]
2055045-04-8 | [Synonyms]
Biotin-PEG6-SPA
CAS_2055045-04-8
(+)-Biotin-PEG6-NHS Ester
(+)-Biotin-PEG6-NHS Ester
4,7,10,13,16,19-Hexaoxa-22-azaheptacosanoic acid, 27-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-23-oxo-, 2,5-dioxo-1-pyrrolidinyl ester | [Molecular Formula]
C29H48N4O12S | [MDL Number]
MFCD22056308 | [MOL File]
2055045-04-8.mol | [Molecular Weight]
676.776 |
| Hazard Information | Back Directory | [Description]
Biotin-PEG6-NHS ester is an amine reactive biotinylation reagent that can couple with amino (-NH2) containing molecule. The NHS group reacts specifically and efficiently with lysine and N-terminal amino groups at pH 7-9 to form stable amide bonds. he hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
Biotin-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
| Company Name: |
T&W GROUP
|
| Tel: |
021-61551611 13296011611 |
| Website: |
www.trustwe.com/ |
|