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2055344-67-5

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2055344-67-5 Structure

2055344-67-5 Structure
IdentificationBack Directory
[Name]

(S,R,S)-AHPC
[CAS]

2055344-67-5
[Synonyms]

(S,R,S)-AHPC
ULM-1(MDK7526
(S,R,S) AHPC,(S,R,S)AHPC
[Molecular Formula]

C23H32N4O3S
[MOL File]

2055344-67-5.mol
[Molecular Weight]

444.59
Chemical PropertiesBack Directory
[Boiling point ]

687.9±55.0 °C(Predicted)
[density ]

1.233±0.06 g/cm3(Predicted)
[pka]

14.00±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

(S,R,S,R)-AHPC-Me serves as a VHL ligand that facilitates the recruitment of the VHL protein.
[IC 50]

VHL
[References]

[1] Jiajun Dong, et al. Small Molecule Degraders of Protein Tyrosine Phosphatase 1B and T-Cell Protein Tyrosine Phosphatase for Cancer Immunotherapy. Angew Chem Int Ed Engl. 2023 May 22;62(22):e202303818. DOI:10.1002/anie.202303818
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