| Identification | Back Directory | [Name]
8-Methylnonanoic acid (4-hydroxy-3-methoxyphenyl)methyl ester | [CAS]
205687-03-2 | [Synonyms]
Dihydrocapsiate
4-Hydroxy-3-Methoxybenzyl 8-Methylnonanoate
(4-hydroxy-3-methoxyphenyl)methyl 8-methylnonanoate
8-Methylnonanoic acid (4-hydroxy-3-methoxyphenyl)methyl este
8-Methylnonanoic acid (4-hydroxy-3-methoxyphenyl)methyl ester
Nonanoic acid,8-methyl-, (4-hydroxy-3-methoxyphenyl)methyl ester | [EINECS(EC#)]
1312995-182-4 | [Molecular Formula]
C18H28O4 | [MDL Number]
MFCD29917840 | [MOL File]
205687-03-2.mol | [Molecular Weight]
308.41 |
| Chemical Properties | Back Directory | [Boiling point ]
413.6±30.0 °C(Predicted) | [density ]
1.038 | [storage temp. ]
Store at -20°C, protect from light | [form ]
Liquid | [pka]
9.51±0.20(Predicted) | [color ]
Colorless to light yellow | [Major Application]
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care | [InChI]
1S/C18H28O4/c1-14(2)8-6-4-5-7-9-18(20)22-13-15-10-11-16(19)17(12-15)21-3/h10-12,14,19H,4-9,13H2,1-3H3 | [InChIKey]
RBCYRZPENADQGZ-UHFFFAOYSA-N | [SMILES]
OC1=C(OC)C=C(COC(CCCCCCC(C)C)=O)C=C1 | [LogP]
5.094 (est) |
| Hazard Information | Back Directory | [Uses]
Dihydrocapsiate, is a complex that is found in chili peppers which has been used in different biological studies to determine the inhibitory effects. This includes the studies performed on cytochrome P 450 3A4 in human liver microsomes. | [Definition]
ChEBI: Dihydrocapsiate is a member of methoxybenzenes and a member of phenols. | [in vivo]
Dihydrocapsiate (2 and 10 mg/kg; p.o.) improves morphometric parameters and insulin levels, prevents high fat diet (HFD)-induced adipocyte size and enhances energy expenditure-related genes in WAT, alleviates HFD-induced hepatic steatosis, prevents HFD-induced fat deposition and enhances mitochondrial biogenesis genes in BAT and improves intestinal morphology and modulates SCFA availability. | Animal Model: | HFD-fed mice[1] | | Dosage: | 2 and 10 mg/kg | | Administration: | P.o. | | Result: | Improved morphometric parameters and insulin levels, prevented HFD-induced adipocyte size and enhanced energy expenditure-related genes in WAT, alleviated HFD-induced hepatic steatosis, prevented HFD-induced fat deposition and enhanced mitochondrial biogenesis genes in BAT and improved intestinal morphology and modulates SCFA availability.
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| [IC 50]
TRPV1 |
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| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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