| Identification | Back Directory | [Name]
6-FLUOR-2-FENYL-9-METHYL-4-(PYRROLIDINE-1-CARBONYL)-9H-PYRIDO[3,4B]INDOOL-1(2H)-ON | [CAS]
205881-86-3 | [Synonyms]
1498
SL65
SL-65
SL 65
SL 651498
6-FLUOR-2-FENYL-9-METHYL-4-(PYRROLIDINE-1-CARBONYL)-9H-PYRIDO[3,4B]INDOOL-1(2H)-ON
1H-Pyrido[3,4-b]indol-1-one, 6-fluoro-2,9-dihydro-9-methyl-2-phenyl-4-(1-pyrrolidinylcarbonyl)-
Pyrrolidine,1-[(6-fluoro-2,9-dihydro-9-methyl-1-oxo-2-phenyl-1H-pyrido[3,4-b]indol-4-yl)carbonyl]- | [Molecular Formula]
C23H20FN3O2 | [MDL Number]
MFCD04113223 | [MOL File]
205881-86-3.mol | [Molecular Weight]
389.42 |
| Chemical Properties | Back Directory | [Boiling point ]
649.7±55.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [solubility ]
DMSO: >100mM | [form ]
A crystalline solid | [pka]
-0.92±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
SL651498 is a full agonist of α2 and α3 GABAA receptors, and a partial agonist of α1 and α5 GABAA receptors. SL651498 shows anxiolytic and anticonvulsant activities[1]. | [References]
[1] G Griebel, et al. SL651498: an anxioselective compound with functional selectivity for alpha2- and alpha3-containing gamma-aminobutyric acid(A) (GABA(A)) receptors. J Pharmacol Exp Ther. 2001 Aug;298(2):753-68. PMID:11454940 |
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BOC Sciences
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https://www.bocsci.com |
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