| Identification | Back Directory | [Name]
Benzenecarbothioic acid, hydrazide | [CAS]
20605-40-7 | [Synonyms]
Benzothiohydrazide
Thiobenzoylhydrazine
Thiobenzoic acid hydrazide
N-aminobenzenecarbothioamide
Benzenecarbothioic acid, hydrazide | [Molecular Formula]
C7H8N2S | [MDL Number]
MFCD00463358 | [MOL File]
20605-40-7.mol | [Molecular Weight]
152.22 |
| Chemical Properties | Back Directory | [Melting point ]
81-82 °C | [Boiling point ]
266.7±23.0 °C(Predicted) | [density ]
1.219±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
8.62±0.70(Predicted) | [color ]
Light yellow to green yellow |
| Hazard Information | Back Directory | [Uses]
Benzothiohydrazide is an analogue of anti–tubercular agent Isoniazid. Benzothiohydrazide exhibits anti–tubercular activity, with MICs of 132 μM and 264 μM for M. tuberculosis wild type (H37Rv) and clinical mutant strains (IC1 and IC2)[1]. | [References]
[1] J. Laborde, et al. Synthesis, oxidation potential and anti–mycobacterial activity of isoniazid and analogues: insights into the molecular isoniazid activation mechanism. ChemistrySelect, 1(2), 172–179. |
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