| Identification | Back Directory | [Name]
9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine | [CAS]
206055-70-1 | [Synonyms]
LNA-A
LNA Adenosine
LNA-Adenosine
4'-C-Methyleneadenosine
2'-O,4'-C-Methyleneadenosine
2'-O,4'-C-Methyleneadenosine
2’-O,4’-C-Methyleneadenosine, LNA-A
9H-Purin-6-amine, 9-[2,5-anhydro-4-C-(hydroxymethyl)-α-L-lyxofuranosyl]-
9-[2,5-Anhydro-4-C-(hydroxymethyl)-alpha-L-lyxofuranosyl]-9H-purin-6-amine | [Molecular Formula]
C11H13N5O4 | [MDL Number]
MFCD18643183 | [MOL File]
206055-70-1.mol | [Molecular Weight]
279.25 |
| Chemical Properties | Back Directory | [Boiling point ]
660.0±65.0 °C(Predicted) | [density ]
2.14±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
12.98±0.60(Predicted) | [color ]
White to off-white | [InChI]
InChI=1/C11H13N5O4/c12-8-5-9(14-3-13-8)16(4-15-5)10-6-7(18)11(1-17,20-10)2-19-6/h3-4,6-7,10,17-18H,1-2H2,(H2,12,13,14)/t6-,7+,10-,11+/s3 | [InChIKey]
GHKDRNDFVCEETA-MIRGOXCMNA-N | [SMILES]
[C@@]12([H])[C@]([H])(O)[C@@](CO)(O[C@H]1N1C3=C(N=C1)C(N)=NC=N3)CO2 |&1:0,2,5,9,r| |
| Hazard Information | Back Directory | [Uses]
2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog[1]. | [Biological Activity]
2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog[1]. | [storage]
Store at -20°C | [References]
[1]. Ravn J, et al. Design, synthesis, and biological evaluation of LNA nucleosides as adenosine A3 receptor ligands. Bioorg Med Chem. 2007 Aug 15;15(16):5440-7. |
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