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206055-81-4

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206055-81-4 Structure

206055-81-4 Structure
IdentificationBack Directory
[Name]

N4-Banzoyl-5-methyl-2'-O,4'-C-methylenecytidine
[CAS]

206055-81-4
[Synonyms]

LNA-N4-Bz-methyl-C
N-benzoyl-5-methyl-2'-O,4'-C-methylene-Cytidine
N4-Benzoyl-5-methyl-2’-O,4’-C-methylenecytidine
N4-Banzoyl-5-methyl-2'-O,4'-C-methylenecytidine
(1S,3R,4R,7S)-7-hydroxy-1-hydroxymethyl-3-(5-methyl-4-N-benzoylcytosine-1-yl)-2,5-dioxabicyclo[2.2.1]heptane
[Molecular Formula]

C18H19N3O6
[MDL Number]

MFCD32215160
[MOL File]

206055-81-4.mol
[Molecular Weight]

373.37
Chemical PropertiesBack Directory
[density ]

1.58±0.1 g/cm3(Predicted)
[pka]

8.62±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

N4-Benzoyl-5-methyl-2’-O,4’-C-methylenecytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
[References]

[1] Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. DOI:10.4161/cbt.3.11.1308
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