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2065250-25-9

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2065250-25-9 Structure

2065250-25-9 Structure
IdentificationBack Directory
[Name]

DAAO inhibitor-1
[CAS]

2065250-25-9
[Synonyms]

DAAO inhibitor-1
2H-Indazol-3-ol, 6-fluoro-
[Molecular Formula]

C7H5FN2O
[MOL File]

2065250-25-9.mol
[Molecular Weight]

152.13
Chemical PropertiesBack Directory
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

DMSO : 125 mg/mL (821.67 mM)
[form ]

Solid
[color ]

Light yellow to yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

DAAO inhibitor-1 is a potent D-amino acid oxidase (DAAO) inhibitor with an IC50 of 0.12 μM.
[References]

[1] Szilágyi B, et al. Discovery of isatin and 1H-indazol-3-ol derivatives as d-amino acid oxidase (DAAO) inhibitors. Bioorg Med Chem. 2018 May 1;26(8):1579-1587. DOI:10.1016/j.bmc.2018.02.004
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