| Identification | Back Directory | [Name]
(S)-1-cyano-N-(4-(6-cyano-5-methoxypyridin-2-yl)thiazol-2-yl)-N-methylpyrrolidine-2-carboxamide | [CAS]
2067332-64-1 | [Synonyms]
USP30 inhibitor 11
USP30 inhibitor 11,USP-30 inhibitor 11
(S)-1-cyano-N-(4-(6-cyano-5-methoxypyridin-2-yl)thiazol-2-yl)-N-methylpyrrolidine-2-carboxamide | [Molecular Formula]
C17H16N6O2S | [MDL Number]
MFCD31714079 | [MOL File]
2067332-64-1.mol | [Molecular Weight]
368.413 |
| Chemical Properties | Back Directory | [Boiling point ]
654.440±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.434±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
0.172±0.10(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
USP30 inhibitor 11 is a selective and potent ubiquitin specific peptidase 30 (USP30) inhibitor with an IC50 of 0.01 μΜ, the example 83 extracted from patent WO2017009650A1. USP30 inhibitor 11 is used for the study of cancer and conditions involving mitochondrial dysfunction[1]. | [References]
[1] Mark Kemp, et al. Cyanopyrrolidines as dub inhibitors for the treatment of cancer. Patent WO 2017009650 A1. |
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