| Identification | Back Directory | [Name]
(3aR)-3-[2-(methylamino)-2-oxoethyl]-2-oxo-1-[(4-phenylphenyl)methyl]-3,4,5,6-tetrahydroindole-3a-carboxylate | [CAS]
2070009-45-7 | [Synonyms]
(3aR)-3-[2-(methylamino)-2-oxoethyl]-2-oxo-1-[(4-phenylphenyl)methyl]-3,4,5,6-tetrahydroindole-3a-carboxylate | [Molecular Formula]
C25H27N2NaO4 | [MOL File]
2070009-45-7.mol | [Molecular Weight]
442.49 |
| Hazard Information | Back Directory | [Uses]
Fumarate hydratase-IN-2 sodium salt (compound 3) is a cell-permeable and competitive fumarate hydratase inhibitor (Ki=4.5 μM) with nutrient-dependent cytotoxicity [1]. | [References]
[1] Takeuchi T et al. Identification of fumarate hydratase inhibitors with nutrient-dependent cytotoxicity. J Am Chem Soc. 2015 Jan 21;137(2):564-7. DOI:10.1021/ja5101257 |
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