ChemicalBook--->CAS DataBase List--->207129-35-9

207129-35-9

207129-35-9 Structure

207129-35-9 Structure
IdentificationBack Directory
[Name]

(1S,2S,5S)-2-(HYDROXYMETHYL)-5-VINYLQUINUCLIDINE
[CAS]

207129-35-9
[Synonyms]

QCI
QUINCORINE
Quincorine >
(1S 2S 5R)-2-HYDROXYMETHYL-5-VINYL- &
(1S,2S,5S)-5-VINYL-2-QUINUCLIDINEMETHANOL
(2S,4S,5R)-5-VINYLQUINUCLIDINE-2-METHANOL
(1S,2S,5R)-5-Vinyl-2-quinuclidinemethanol
((1S,2S,5S)-5-Vinylquinuclidin-2-yl)methanol
(2S,4S,5R)-2-HYDROXYMETHYL-5-VINYLQUINUCLIDINE
(1S,2S,5R)-2-Hydroxymethyl-5-vinylquinuclidine
(1S,2S,5S)-2-(HYDROXYMETHYL)-5-VINYLQUINUCLIDINE
(1S,2S,4S,5R)-5-Ethenyl-1-azabicyclo[2.2.2]octane-2-methanol
1-Azabicyclo[2.2.2]octane-2-Methanol,5-ethenyl-, (1S,2S,4S,5R)-
(1S,2S,5R)-5-Vinyl-2-quinuclidinemethanol,(sum of enantiomers,GC)
(1S,2S,5S)-2-(Hydroxymethyl)-5-vinylquinuclidine (1S,2S,5S)-5-Vinyl-2-quinuclidinemethanol
[Molecular Formula]

C10H17NO
[MDL Number]

MFCD08276491
[MOL File]

207129-35-9.mol
[Molecular Weight]

167.25
Chemical PropertiesBack Directory
[Melting point ]

25-27 °C(lit.)
[Boiling point ]

270 °C(lit.)
[density ]

1.051 g/mL at 20 °C(lit.)
[refractive index ]

39 ° (C=1, MeOH)
[storage temp. ]

2-8°C
[form ]

powder to lump to clear liquid
[pka]

14.70±0.10(Predicted)
[color ]

White or Colorless to Yellow
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[HS Code ]

2933.99.9701
Questions And AnswerBack Directory
[Application]

In 1820, it was first isolated and purified from quina bark powder and proved to be an effective drug for treating malaria. In addition to its medicinal value, quinine is also an important chiral catalyst in the field of organic synthesis and is widely used in the field of asymmetric catalysis of small organic molecules.
Hazard InformationBack Directory
[Synthesis]

TBAF (1M solution of THF, 37 μL, 0.037 mmol) was added to a solution of 21c (8 mg, 0.028 mmol) in THF (1 mL) at 0 °C. The solution was allowed to warm to ambient temperature. concentrated after 12 h. (1S,2S,5S)-2-(hydroxymethyl)-5-vinylquinuclidine ring (
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