| Identification | Back Directory | [Name]
1-(2,3,5-Tri-O-benzoyl-4-thio-beta-D-ribofuranosyl)uracil | [CAS]
2072145-30-1 | [Synonyms]
2',3',5'-Tri-O-Benzoyl-4'-thiouridine
1-(2,3,5-Tri-O-benzoyl-4-thio-beta-D-ribofuranosyl)uracil
(2R,3S,4R,5R)-2-((benzoyloxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrothiophene-3,4-diyl dibenzoate | [Molecular Formula]
C30H24N2O8S | [MDL Number]
MFCD22666334 | [MOL File]
2072145-30-1.mol | [Molecular Weight]
572.585 |
| Hazard Information | Back Directory | [Uses]
2’,3’,5’-Tri-O-benzoyl-4’-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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