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2072145-35-6

2072145-35-6 Structure

2072145-35-6 Structure
IdentificationBack Directory
[Name]

6-Methoxy-9-(3-deoxy-3-fluoro--D-ribofuranosyl)-9H-purine
[CAS]

2072145-35-6
[Synonyms]

6-Methoxypurine-9-β-D-(3’-deoxy-3’-fluoro)riboside
6-Methoxy-9-(3-deoxy-3-fluoro--D-ribofuranosyl)-9H-purine
6-Methoxy-9-(3-deoxy-3-fluoro-b-D-ribofuranosyl)-9H-purine
6-Methoxy-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine
[Molecular Formula]

C11H13FN4O4
[MOL File]

2072145-35-6.mol
[Molecular Weight]

284.25
Chemical PropertiesBack Directory
[Boiling point ]

567.6±60.0 °C(Predicted)
[density ]

1.79±0.1 g/cm3(Predicted)
[pka]

12.42±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

6-Methoxy purine-9-beta-D-(3’-deoxy-3’-fluoro)riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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