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2072145-60-7

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2072145-60-7 Structure

2072145-60-7 Structure
IdentificationBack Directory
[Name]

5-Iodo-2'-C-Methyl cytidine
[CAS]

2072145-60-7
[Synonyms]

5-Iodo-2'-C-Methyl cytidine
5-Iodo-2’-β-C-methyl cytidine
5-Iodo-2’-C-methyl cytidine, 5-Iodo-2’-C-methyl-1-β-D-ribofuranosylcytosine
[Molecular Formula]

C10H14IN3O5
[MDL Number]

MFCD25542501
[MOL File]

2072145-60-7.mol
[Molecular Weight]

383.14
Chemical PropertiesBack Directory
[Boiling point ]

549.0±60.0 °C(Predicted)
[density ]

2.29±0.1 g/cm3(Predicted)
[pka]

13.53±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

5-Iodo-2’-β-C-methyl cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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