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2072145-81-2

2072145-81-2 Structure

2072145-81-2 Structure
IdentificationBack Directory
[Name]

2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-Methoxyluridine
[CAS]

2072145-81-2
[Synonyms]

2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine
2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methoxyuridine
2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-Methoxyluridine
[Molecular Formula]

C20H21FN2O8
[MDL Number]

MFCD27921031
[MOL File]

2072145-81-2.mol
[Molecular Weight]

436.39
Chemical PropertiesBack Directory
[density ]

1.41±0.1 g/cm3(Predicted)
[pka]

8?+-.0.10(Predicted)
Hazard InformationBack Directory
[Uses]

2’-O-Acetyl-5’-O-(p-toluoyl)-3’-deoxy-3’-fluoro-5-methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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