| Identification | Back Directory | [Name]
Resorantel | [CAS]
20788-07-2 | [Synonyms]
RESORANTEL
Pesorantelum
N-(4-Bromophenyl)-2,6-dihydroxybenzamide
Benzamide, N-(4-bromophenyl)-2,6-dihydroxy- | [EINECS(EC#)]
244-040-9 | [Molecular Formula]
C13H10BrNO3 | [MDL Number]
MFCD00864511 | [MOL File]
20788-07-2.mol | [Molecular Weight]
308.13 |
| Chemical Properties | Back Directory | [Melting point ]
229-230°; mp 183-186° (LeMaire) | [Boiling point ]
391.1±42.0 °C(Predicted) | [density ]
1.699±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO : 250 mg/mL (811.35 mM; Need ultrasonic) | [form ]
Solid | [pka]
7.62±0.35(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Resorantel is an anthelmintic[1]. Resorantel is used in the research of paramphistomiasis in cattle and sheep and has also been used for the research of G. aegypticus[2]. | [in vivo]
Resorantel (65 mg/kg, a single oral dose) possesses efficacy against paramphistomiasis in naturally infected sheep[1]. | Animal Model: | Five flocks of sheep in different villages of Haryana[1]. | | Dosage: | 65 mg/kg. | | Administration: | A single oral dose. | | Result: | None of the treated sheep died of enteric paramphistomiasis. The clinical signs disappeared within 2 to 3 days of the treatment and their appetite and general condition improved. No ill effects of the drug were noticed. Of the untreated sheep, 35 % died with a range of 24-52 % in the different flocks. Many of the other untreated sheep continued to exhibit clinical signs of paramphistomiasis. |
| [storage]
Store at -20°C | [References]
[1] R P Gupta, et al. Efficacy of resorantel against paramphistomiasis in naturally infected sheep. Trop Anim Health Prod. 1981 Feb;13(1):35-6. DOI:10.1007/BF02237884
[2] Swan GE. The pharmacology of halogenated salicylanilides and their anthelmintic use in animals. J S Afr Vet Assoc. 1999;70(2):61-70. DOI:10.4102/jsava.v70i2.756 |
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Aemon Chemical
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www.aemonchem.com |
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AFINE CHEMICALS LIMITED
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www.afinechem.com/index.html |
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