| Identification | Back Directory | [Name]
RSMZOLWJZGIWOV-CZIZESTLSA-N | [CAS]
2080311-92-6 | [Synonyms]
RSMZOLWJZGIWOV-CZIZESTLSA-N
2,5-Cyclohexadiene-1,4-dione, 5-cyclohexyl-2-methyl-, 1-[O-(phenylsulfonyl)oxime] | [Molecular Formula]
C19H21NO4S | [MOL File]
2080311-92-6.mol | [Molecular Weight]
359.44 |
| Chemical Properties | Back Directory | [Boiling point ]
500.1±53.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [solubility ]
Soluble to 50 mM in DMSO | [form ]
Solid | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
ML233 is a non-peptide based potent apelin receptor (APJ) agonist (EC50=3.7 μM). ML233 displays >21-fold selective over the closely related angiotensin 1 (AT1) receptor (>79 μM)[1]. | [storage]
Store at -20°C | [References]
[1] Khan P, et al. National Center for Biotechnology Information; 2011. Functional agonists of the apelin (APJ) receptor. In Probe Reports from the NIH Molecular Libraries Program. PMID:22834038
[2] Pasha Khan, et al. National Center for Biotechnology Information; 2011. Functional agonists of the apelin (APJ) receptor. In Probe Reports from the NIH Molecular Libraries Program. PMID:22834038 |
|
|