| Identification | Back Directory | [Name]
N2-iso-Buty royl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoroguanosine | [CAS]
2080404-19-7 | [Synonyms]
5'-O-DMTr-3'-F-N6-iBu-3'-deoxy-Guanosine
N2-iso-Buty royl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoroguanosine
Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-3'-fluoro-N-(2-methyl-1-oxopropyl)-
N-[9-[(2R,3S,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-fluoro-3-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide | [Molecular Formula]
C35H36FN5O7 | [MDL Number]
MFCD31556780 | [MOL File]
2080404-19-7.mol | [Molecular Weight]
657.69 |
| Hazard Information | Back Directory | [Uses]
N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1]. | [References]
[1] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100 |
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