| Identification | Back Directory | [Name]
1H-Benzimidazolium, 2-[[[(3-amino-6-chloro-2-pyrazinyl)carbonyl]amino]methyl]-5-[[[2-(dimethylamino)ethyl]methylamino]carbonyl]-1,3-diethyl-, chloride (1:1) | [CAS]
2084059-97-0 | [Synonyms]
BI-8668
1H-Benzimidazolium, 2-[[[(3-amino-6-chloro-2-pyrazinyl)carbonyl]amino]methyl]-5-[[[2-(dimethylamino)ethyl]methylamino]carbonyl]-1,3-diethyl-, chloride (1:1) | [Molecular Formula]
C23H32ClN8O2.Cl | [MOL File]
2084059-97-0.mol | [Molecular Weight]
523.46 |
| Hazard Information | Back Directory | [Uses]
BI-8668 (compound 40) is an inhibitor of ENaC. BI-8668 can be used in the study of cystic fibrosis[1]. | [References]
[1] Betzemeier B, et al. Discovery and development of BI 1265162, an ENaC inhibitor for the treatment of cystic fibrosis. Eur J Med Chem. 2023 Dec 18;265:116038. DOI:10.1016/j.ejmech.2023.116038 |
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