| Identification | Back Directory | [Name]
D-Xylitol, 1,5-anhydro-2,4-dideoxy-2-(3,6-dichloro-9H-carbazol-9-yl)-4-[[[4-(trifluoromethoxy)phenyl]sulfonyl]amino]- | [CAS]
2088956-21-0 | [Synonyms]
Anticancer agent 7
D-Xylitol, 1,5-anhydro-2,4-dideoxy-2-(3,6-dichloro-9H-carbazol-9-yl)-4-[[[4-(trifluoromethoxy)phenyl]sulfonyl]amino]- | [Molecular Formula]
C24H19Cl2F3N2O5S | [MOL File]
2088956-21-0.mol | [Molecular Weight]
575.38 |
| Chemical Properties | Back Directory | [Boiling point ]
661.9±65.0 °C(Predicted) | [density ]
1.62±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
9.58±0.60(Predicted) | [color ]
Off-white to pink |
| Hazard Information | Back Directory | [Uses]
Anticancer agent 7 (Example 5) modulates PP2A, and induces FOXOl transcription factor translocation to the nucleus. Anticancer agent 7 inhibits the proliferation of H1650 lung cancer cell with an IC50 of 5 μM[1]. | [References]
[1] Michael Ohlmeyer, et al. Heterocyclic constrained tricyclic sulfonamides as anti-cancer agents. WO2017044569A1. |
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